Further Studies of Avian Osteopetrosis Virus

Comparison of an avian osteopetrosis virus with an avian lymphomatosis virus by RNA-DNA hybridization.

Myeloblastosis-associated virus (MAV)-2(0), a virus which was derived from avian myeloblastosis virus and induced a high incidence of osteopetrosis, was compared with avian lymphomatosis virus 5938, a recent field isolate which induced a high incidence of lymphomatosis. The following information was obtained. (i) MAV-2(0) induced osteopetrosis, nephroblastoma, and a very low incidence of hepato...

Biological characterization of avian osteopetrosis.

Chicks infected as 12-day-old embryos with an end-point purified derivative of avian myeloblastosis virus developed a rapidly progressive osteopetrosis that manifested within 1 week of hatching. A detailed comparison of osteopetrotic chicks and normal hatchmates revealed the following. (i) Osteopetrotic chicks exhibited a stunting syndrome, growing at a mean rate that was 26% of the control rat...

Studies in Osteopetrosis.

Experimental Studies of the Virus of Infectious Avian Encephalomyelitis

The results of investigations thus far carried out on experimental avian encephalomyelitis indicate that the virus of this newly described disease conforms to the group of definitely established viruses. It was essential to determine its taxonomy since the only prior record of its study (1) defines the infective agent as a virus because the usual cultural attempts failed to reveal a visible mic...

Standardization of ELISA for Detection of Avian Influenza Virus Antibodies